Here's a review covering new evidence that a phase separating protein forms condensates that facilitate "branched microtubule nucleation." If you're wondering what that means (I didn't know either) check out the text for further details.

The FEBS Journal

Alternative systems for misfolded protein clearance: life beyond the proteasome

Jill Bouchard

Contributing editor, Condensates.com

This review discusses the role of phase separation in accumulating misfolded proteins into the various membraneless organelles that are part of a cell's proteostasis network.

bioRxiv

Ligand Effects on Phase Separation of Multivalent Macromolecules

Nature

RNA nucleation by MSL2 induces selective X chromosome compartmentalization

Jill Bouchard

Contributing editor, Condensates.com

It looks like low complexity sequences and non-coding RNA are important for condensing chromosomes. I wonder if interactions are important in chromatin condensates?

BioRxiv

Event

Dec

10

The Protein Society Webinar #5: Liquid-liquid Phase Separation (LLPS) of Proteins and Their Role in Pathology

Thursday, December 10, 2020

Nucleosome plasticity is a critical element of chromatin liquid–liquid phase separation and multivalent nucleosome interactions

Splicing modulators elicit global translational repression by condensate-prone proteins translated from introns

VIB Online Course on Liquid-Liquid Phase Separation

Intern, Administrative and Laboratory Operations (m/f/d)

Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis

Complex Morphogenesis by a Model Intrinsically Disordered Protein

Review: F-Actin remodelling during plant signal transduction via biomolecular assembly

Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins

Fassberg Seminar – Special Date: Biomolecular condensates and their implications for physiology and disease

Metabolic Compartmentalization at the Leading Edge of Metastatic Cancer Cells

Identification and Characterization of the Heat-Induced Plastidial Stress Granules Reveal New Insight Into Arabidopsis Stress Response

Thermostabilization of viruses via complex coacervation

Microtubule nucleation: The waltz between γ-tubulin ring complex and associated proteins

Jill Bouchard

Alternative systems for misfolded protein clearance: life beyond the proteasome

Jill Bouchard

Ligand Effects on Phase Separation of Multivalent Macromolecules

RNA nucleation by MSL2 induces selective X chromosome compartmentalization

Jill Bouchard

Genome-wide maps of nucleolus interactions reveal distinct layers of repressive chromatin domains

Assembly of synaptic active zones requires phase separation of scaffold molecules

Generalist, People & Culture Team

The Protein Society Webinar #5: Liquid-liquid Phase Separation (LLPS) of Proteins and Their Role in Pathology

Intern, Administrative and Laboratory Operations (m/f/d)

Generalist, People & Culture Team

Senior Director/VP, New Product Strategy