Sep
15
Broder Schmidt on Targeting Intrinsically Disordered Proteins (IDPs): In the Pack vs. the Lone Wolf
Wednesday, September 15, 2021
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Research Associate – Oncology (m/f/d)
Dewpoint Therapeutics | Dresden, Germany
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Dewpoint Therapeutics | Dresden, Germany
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03
Condensate Colloquium Series: Jerelle Joseph & Saumya Saurabh — August 3
Tuesday, August 3, 2021
Aug
05
IDPSeminars: Rebecca Beveridge & Carlos Castañeda — August 5
Thursday, August 5, 2021
Assoc. Director/Director – Project Management (m/f/d)
Dewpoint Therapeutics | Dresden, Germany
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University of Copenhagen | Copenhagen, Denmark
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Dewpoint Therapeutics | Boston, MA, USA
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Dewpoint Therapeutics | Boston, MA, USA
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Structure insights, thermodynamic profiles, dsDNA melting activity, and liquid-liquid phase separation of the SARS-CoV-2 nucleocapsid N-terminal domain binding to DNA
Proceedings of the National Academy of Sciences of the United States of America
Glucocorticoid receptor condensates link DNA-dependent receptor dimerization and transcriptional transactivation
JCI insight
Characterization of HNRNPA1 mutations defines diversity in pathogenic mechanisms and clinical presentation
Biochemistry
Liquid-Liquid Phase Separation in Biology: Specific Stoichiometric Molecular Interactions vs Promiscuous Interactions Mediated by Disordered Sequences
The journal of physical chemistry letters
Interplay between Kinetics and Dynamics of Liquid-Liquid Phase Separation in a Protein Solution Revealed by Coherent X-ray Spectroscopy
Journal of the American Chemical Society
Different Folding States from the Same Protein Sequence Determine Reversible vs Irreversible Amyloid Fate
Jill Bouchard
Managing editor, Condensates.com
This work argues amyloids can be reversible and irreversible.
Journal of virology
EV71 2A Protease inhibits P-body formation to promote viral RNA synthesis
Jill Bouchard
Managing editor, Condensates.com
I see a lot of interesting work about the role of stress granules in viral infections. This work looks at P bodies. Check out this paper for a fresh take on condensates in infections.
The EMBO journal
Tudor staphylococcal nuclease is a docking platform for stress granule components and is essential for SnRK1 activation in Arabidopsis
Jill Bouchard
Managing editor, Condensates.com
We saw this paper come out on bioRxiv last year, and it's nice to see it published in EMBO J now! Check out our post about the original bioRxiv preprint here.
bioRxiv
Regulation of a bacterial histidine kinase by a phase separating scaffolding protein
Nature communications
High-depth spatial transcriptome analysis by photo-isolation chemistry
Jill Bouchard
Managing editor, Condensates.com
This looks to be a useful new method to detect genes expressed in condensates.
Biochimica et biophysica acta Molecular cell research