bioRxiv
Most Recent
Annals of clinical and translational neurology
Neuronal RNA-binding Protein Dysfunction in Multiple Sclerosis Cortex
Jill Bouchard
Contributing editor, Condensates.com
These authors found a continuum of phenotypes in the mislocalization of RNA-binding proteins in MS neurons. Understanding the patterns (and how stress granules are involved) will help shed light on disease progression and severity.
The Journal of cell biology
Conserved Metabolite Regulation of Stress Granule Assembly via AdoMet
The Journal of cell biology
Tyramide Signal Amplification Mass Spectrometry (TSA-MS) Ratio Identifies Nuclear Speckle Proteins
bioRxiv
Phosphorylation modulates liquid-liquid phase separation of the SARS-CoV-2 N protein
Cancer science
Nuclear Microenvironment in Cancer: Control Through Liquid-Liquid Phase Separation
The Journal of cell biology
Liquid-liquid Phase Separation in Autophagy
Plants (Basel, Switzerland)
Late Embryogenesis Abundant Protein-Client Protein Interactions
Jill Bouchard
Contributing editor, Condensates.com
These authors propose that plants may use LLPS for protection during stressful situations.
Proceedings of the National Academy of Sciences of the United States of America
Enzymatic Degradation of Liquid Droplets of DNA Is Modulated Near the Phase Boundary
Nature chemical biology
Formation and Functionalization of Membraneless Compartments in Escherichia Coli
Postdoctoral Fellow in RNA Microscopy Lab – Trcek Lab
Johns Hopkins University | Baltimore, MD
ApplyNeural regeneration research
Prion-like Domain Disease-Causing Mutations and Misregulation of Alternative Splicing Relevance in Limb-Girdle Muscular Dystrophy (LGMD) 1G
Prion
Prion Domains as a Driving Force for the Assembly of Functional Nanomaterials
bioRxiv
Synthetic liquid-liquid phase separated RNA-protein biocondensates reveal a bi-phasic cytosol in E.coli
Postdoc and graduate student positions – Cai Lab
Johns Hopkins Bloomberg School of Public Health | Baltimore, MD
ApplyCurrent topics in developmental biology
Organizing the Oocyte: RNA Localization Meets Phase Separation
Lab on a Chip
Multidimensional Protein Characterisation Using Microfluidic Post-Column Analysis
Frontiers in molecular biosciences
Interactions by Disorder – A Matter of Context
Jill Bouchard
Contributing editor, Condensates.com
This review discusses how phase separation changes the context of interactions for IDPs.
Soft matter
Phase Behaviour and Structure of a Model Biomolecular Condensate
Langmuir : the ACS journal of surfaces and colloids
Fission and Internal Fusion of Protocell With Membraneless “Organelles” Formed by Liquid-Liquid Phase Separation
Jill Bouchard
Contributing editor, Condensates.com
Here's a strategy to create hierarchical protocells using phase separation and might give us insights into what early life looked like.