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Comments

"This paper shows that ovotestis infertility results from the proteasomes phase separating and causing female germline cells to be degraded."

Cellular fate of intersex differentiation

"This should be a nice breakdown of several methods that can be good for characterizing condensate-loving IDPs."

Integrating single-molecule spectroscopy and simulations for the study of intrinsically disordered proteins

"This review discusses the evolutionary implications of all of ATP's effects on phase separation and protein folding/stability."

ATP energy-independently controls protein homeostasis with unique structure and diverse mechanisms

"Here's a nice review about the role of mutations in RNA-binding proteins that causes dysfunction of various membraneless organelles."

RNA-Binding Proteins and the Complex Pathophysiology of ALS

"I like that these authors analyzed both intrinsic disorder and LLPS propensity of proteins with disease mutations. Check out their results!"

The Participation of the Intrinsically Disordered Regions of the bHLH-PAS Transcription Factors in Disease Development