View Your Favorites

    Access your saved content with one easy click.

    My Favorites

    Save Your Favorites

    Subscribe for free to save your favorites and view a personalized view of content.

    Subscribe for Free

    Be a Contributor

    Submit new content suggestions for Condensates.com.

    Contribute

Condensate News: Research explains how nucleolus sub-compartments drive ribosome assembly

Cells must produce ribosomes efficiently and accurately in order to function and grow properly. This process takes place in the nucleulus, a complex, multilayered condensate composed of thousands of types of biomolecules. A study from Dr. Richard Kriwacki’s lab at St. Jude Children’s Research Hospital in Memphis TN, shows that spatial heterogeneity inside the outer layer of the nucleolus — called the granular component, serves an important function in coordinating the assembly and release of ribosomal subunits.

These findings build experimental support for the model of the nucleolus as an active, multizone manufacturing environment.

Learn more about this topic in this Research Highlights article.

Read the study in full: Dogra P, et al, Molecular Cell (2026).

Image credit: Dogra P, et al, Molecular Cell (2026).