The Protein Folding Dynamics GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

While many of the basic features of in vitro folding are understood thanks to decades of experimental, computational and theoretical work, the process remains a complex one with many facets important for understanding protein evolution, creating new biomedical applications, and building up a dynamical picture of the full proteome. In this conference, we will bring together leading experts in protein science who study structure from disordered proteins to large membrane assemblies, dynamics from nanoseconds to days, misfolding and aggregation, protein-protein interactions from complexes to phase-separated regions in the context of evolution, dynamics, and cell biology. Topics range widely from amyloids to proteins in extreme environments to phase separation. We try to understand the principles behind protein design, structure prediction of dynamical complexes, interaction of proteins with drug molecules, and many other facets where protein dynamics and folding play a critical role.