Loading Events
  • This event has passed.

Phase Separation in Biology and Disease

Event Date February 20, 2019
Time
8:30 am - 5:00 pm - EST
Tags
Website https://www.nyas.org/events/2019/phase-separation-in-biology-and-disease/
Organizers the Chemical Biology Discussion Group
Venue The New York Academy of Sciences
Location
7 World Trade Center, 250 Greenwich St, Fl 40
New York, NY United States

+ Google Map

This one day symposium will bring together scientists from academia and industry to dissect the latest advances in the field of biological phase separation and discuss the implications for human disease.

 

Liquid-liquid phase separation of cytoplasmic and nuclear components into biomolecular condensates is emerging as a fundamental mechanism of cellular organization. These condensates are spatially segregated, but open systems, which can serve as specialized regions for biochemical reactions, dynamically sequester components or act as organizational hubs for signaling networks.

Phase separation regulates processes as diverse as transcription, stress granule formation and actin polymerization. Moreover, an accumulating body of evidence suggests that dysregulation of these phase transitions may contribute to neurodegenerative diseases, including ALS and prion diseases, as well as to cancer.

 

Available via webinar!