Liquid phase separation into two or more coexisting phases has emerged as a new paradigm for understanding subcellular organization, prebiotic life, and the origins of disease. The design principles underlying biomolecular phase separation has the potential to drive the development of novel liquid-based organelles and targeted therapeutics, however, an understanding of how individual molecules contribute to emergent material properties, and approaches to directly manipulate phase dynamics are lacking. Our group employs quantitative rheological approaches to define condensate material properties and their modulation. I will discuss how we leverage these approaches to bridge the gap between molecular level interactions and emergent properties such as viscosity and the dynamics of multiphase condensates.

Talk by:
Shana Elbaum-Garfinkle
City University of New York

Start time in various timezones:
7:00 am PDT
9:00 am CDT
10:00 am EDT
2:00 pm GMT
3:00 pm CET

Note, this event has passed, but we’ve got you covered:
See the video here.

Create an Account or Sign In to register for the talk.