This virtual FASEB Science Research Conference (SRC) is focused on exploring the biology associated with protein aggregation in terms of diseases (e.g. neurodegenerative and systemic amyloidoses) and normal biological functions (e.g. signal transduction and scaffolding), including the relationships between amyloids and biomolecular condensates.

The conference will bring together primarily academic researchers covering a range of approaches, from fundamental biology to clinical application.

Program

This virtual meeting’s main themes are: 1) Latest findings in the field of protein aggregation, including functional and pathological amyloids and other protein assemblies, and phase separation into biomolecular condensates; 2) Mechanisms of disease; 3) Therapeutic design and clinical strategies.

Conference sessions will present the latest research and foster discussion on:

• Structure and assembly mechanisms of protein aggregates
• Systemic amyloidosis and prions
• Protein phase separation
• Biophysical processes underpinning aggregation
• Neurodegeneration pathomechanisms
• New technologies in the field
• Therapeutic strategies
• Proteostasis
• Proteotoxicity
• Functional aggregates
• Clinical strategies

The conference covers 12 sessions with 25 selected abstract presentations, a series of “Meet the Expert” sessions held informally over lunch, and career development workshops. We are delighted to have Don Cleveland, PhD (University of California, San Diego) present the keynote lecture and Anne Bertolotti, PhD, MRC Laboratory of Molecular Biology present the EMBO Lecture during the conference.