Biomolecular condensates are an emerging class of intracellular membrane-less organelles and are primarily formed by liquid-liquid phase separation of multivalent intrinsically disordered protein-RNA complexes. In this presentation, I will discuss our latest findings on the mechanism, dynamics, and topologies of cellular phase-separated condensates using appropriate model systems. A particular focus will be placed on deciphering the emergent structure and dynamics of biomolecular condensates by the application of correlative fluorescence microscopy and optical
tweezers.

Instructor:
Priya R. Banerjee, PhD
Department of Physics, University at Buffalo, Buffalo NY 14260, USA
Email: prbanerj@buffalo.edu

Costs: Free of charge
Duration: 45 minutes
Language: English