Johns Hopkins University
We are looking for a postdoctoral fellow or research associate to join the Leung Lab at the Johns Hopkins University. We will dissect the biochemistry of biomolecular condensate regulation by poly(ADP-ribose).
Poly(ADP-ribose) is a therapeutically important protein modification as evidenced by the FDA approval of poly(ADP-ribose) polymerase inhibitor for treating cancers. Here, we will investigate the condensate biology, specifically RNA-enriched granules, in viral infection and/or neurodegeneration. Our ultimate goal is to translate basic scientific discovery to biomarkers or therapeutic targets.
The ideal candidate should have prior experiences in biochemistry using various affinity purification techniques and protein purification techniques. Experiences with proteomics, post-translational modifications, nucleic acid chemistry, or relevant disease biology are a plus.
Interested candidates should send a cover letter briefly describing their career goals/research interests (0.5 page) and accomplishments (0.5 page) to Anthony. The candidate’s CV and contact information for 3 references should also be provided for consideration.
We are a team from diverse backgrounds, with expertise in molecular biology, cell biology, biochemistry, proteomics, chemistry, and informatics. Over the years, our team has developed novel techniques to investigate poly(ADP-ribose) and discovered its roles in controlling condensate formation, disassembly, and composition. Therefore, these insights provide us a unique edge in exploring the science and developing the candidate for their next career move.
The Johns Hopkins University provides an excellent and stimulating scientific environment for collaboration and exchange of ideas to pursue our research goals .
We enjoy a rich diversity of faculty research programs in the following departments that apply basic molecular, cellular and biochemical approaches to fundamental issues in public health and medicine:
- We are a part of the Department of Biochemistry and Molecular Biology—one of the founding departments of Johns Hopkins Bloomberg School of Public Health, which held the #1 spot amongst all schools of public health in the U.S. News & World Report ranking since 1994.
- Our laboratory is also affiliated with the Department of Molecular Biology and Genetics and Department of Genetic Medicine as well as the Sidney Kimmel Comprehensive Cancer Center in the School of Medicine, Johns Hopkins University.
Seminars, journal clubs, and research colloquia where individual laboratories present their latest research are held over the academic years, thus providing a strong environment for candidates to pursue innovative projects.