PhD position – Loquet Lab

PhD position in structural biology of infectious protein assemblies using solid-state NMR

This PhD project is focused on exploring the role and the assembly mechanism of several protein assemblies involved in infectious processes in humans and during bacterial infection. We will use solid-state NMR spectroscopy, in combination with cryo-electron microscopy and X-ray crystallography, to decipher the architecture, ultimately at atomic resolution, of challenging biomolecular assemblies.

Our research focuses on structural biology and biophysics of biological assemblies, ranging from functional amyloids to bacterial nanomachines and lipid membranes. We develop and mainly apply solid-state NMR spectroscopy to capture structural and dynamic details at atomic resolution.

Our group is part of the CBMN, a joint research unit of the CNRS, University of Bordeaux and Bordeaux INP. We are located at the European Institute of Chemistry and Biology. We manage the NMR platform of the IECB / CBMN, which is a part of the national network of high-field NMR TGIR-RMN-THC Fr3050 CNRS.