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Must Reads

Nature cell biology

The STING phase-separator suppresses innate immune signalling

  • Infectious Disease
  • Phase Separation
  • Physics of Condensates

Cell

Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules

  • Cancer
  • Physics of Condensates

Nature Cell Biology

Liquid-like protein interactions catalyse assembly of endocytic vesicles

  • Phase Separation
  • Physics of Condensates

Kitchen Table Talk

VIDEO: Shana Elbaum-Garfinkle on Emergent Material Properties of Biomolecular Condensates

  • Methods
  • Neurodegeneration
  • Phase Separation
  • Physics of Condensates
  • Transcription

Nature

DNA-driven condensation assembles the meiotic DNA break machinery

  • Phase Separation

Nature cell biology

TGF-β-induced DACT1 biomolecular condensates repress Wnt signalling to promote bone metastasis

  • Cancer
  • Metabolism
  • Methods
  • Phase Separation
  • Physics of Condensates

Annual review of plant biology

Biological Phase Separation and Biomolecular Condensates in Plants

  • Phase Separation
  • Physics of Condensates

Nature Reviews, Neuroscience

Triad of TDP43 control in neurodegeneration: autoregulation, localization and aggregation

  • Neurodegeneration
  • Phase Separation
  • Physics of Condensates

Kitchen Table Talk

VIDEO: Huaiying Zhang on Liquid-Liquid Phase Separation in Telomere Maintenance of ALT Cancer

  • Cancer
  • Imaging
  • Methods
  • Phase Separation
  • Physics of Condensates
  • Transcription

Nature Biotechnology

Drug startups coalesce around condensates

  • Artificial Intelligence
  • Cancer
  • Imaging
  • Neurodegeneration
  • Phase Separation
  • Physics of Condensates
  • Transcription

Cell

NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function

  • Methods
  • Phase Separation
  • Physics of Condensates

Jill Bouchard

Managing editor, Condensates.com

Check it out--this review has a nice section on how to study phase separating IDPs.

Kitchen Table Talk

VIDEO: Serena Sanulli on Chromatin and its Phases

  • Cancer
  • Imaging
  • Methods
  • Neurodegeneration
  • Phase Separation
  • Physics of Condensates
  • Transcription

Nature reviews Molecular cell biology

Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing

  • Cancer
  • Neurodegeneration
  • Phase Separation
  • Physics of Condensates
  • Transcription

Webinar

VIRTUAL Genetics Seminar: Anthony Hyman – “Biomolecular condensates in cell physiology and disease”

  • Phase Separation
  • Physics of Condensates

Nature

Wetting regulates autophagy of phase-separated compartments and the cytosol

  • Phase Separation
  • Physics of Condensates

Cancer cell

Biomolecular condensates and cancer

  • Cancer
  • Neurodegeneration
  • Phase Separation
  • Physics of Condensates

A Newfound Source of Cellular Order in the Chemistry of Life

  • Neurodegeneration
  • Phase Separation
  • Physics of Condensates
  • Transcription

Cell

Phase Separation as a Missing Mechanism for Interpretation of Disease Mutations

  • Cancer
  • Phase Separation
  • Physics of Condensates

Science

HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells

  • Neurodegeneration
  • Phase Separation
  • Physics of Condensates
  • Transcription

Cell

RNA-Mediated Feedback Control of Transcriptional Condensates

  • Phase Separation
  • Physics of Condensates
  • Transcription

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IDPfun webinars: Zsuzsanna Dosztanyi & Nicolás Palopoli — April 23

April 23 @ 5:00 pm - 6:00 pm UTC+1
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April 26 @ 3:00 pm UTC+2

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