Most Recent
Brain sciences
Editor in Chief, Condensates.com
Interesting... I never expected to see a protein involved in breast cancer show up in neurodegeneration aggregates. BRCA1 is probably trying to help and unable, but I wonder if mutations are involved?
bioRxiv
Editor in Chief, Condensates.com
An interesting theoretical treatment to consider: micro-phase separated droplets may be the real drivers of the activity of condensates.
Current opinion in plant biology
Journal of molecular biology
Editor in Chief, Condensates.com
I wonder if this method could be used to study condensates interacting with the membrane?
Journal of chemical theory and computation
Editor in Chief, Condensates.com
I wonder if this new force field could be used to study how proteins interact in condensates?
Cell reports
Editor in Chief, Condensates.com
These things go to cytoplasmic condensates distinct from P bodies...I wonder what they are?
Scientific reports
Editor in Chief, Condensates.com
Interesting! Disordered regions made proteins more susceptible to PROTAC-induced degredation. Could this be useful for targetting IDPs in condensates?
Proceedings of the National Academy of Sciences of the United States of America
Editor in Chief, Condensates.com
This is quite the impressive use of advanced techniques to gain insights into clusters of proteins at the ER.
bioRxiv
Editor in Chief, Condensates.com
This is another nice step forward in predicting phase separation propensity of disordered proteins.
Nature communications
Editor in Chief, Condensates.com
This opens up the possibility of targeting condensates to treat colorectal cancer.
Chemistry (Weinheim an der Bergstrasse, Germany)
Editor in Chief, Condensates.com
This is a cool article exploring the pressure sensitivity of condensates in synapses of deep sea creatures.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Editor in Chief, Condensates.com
This is a nice model system to screen if drugs can pass the blood-brain barrier. Plus the resulting drug lead affected condensates in cells. Double cool!
Biochimica et biophysica acta Molecular cell research
Editor in Chief, Condensates.com
An important cautionary note to use appropriate reagents when studying SC35/nuclear speckles.
Journal of cellular physiology
Editor in Chief, Condensates.com
The affects on NEAT1 must have also have an impact on paraspeckles.
Microbial pathogenesis
Editor in Chief, Condensates.com
An interesting link between protein disorder and a virus's ability to jump hosts. I wonder how this variability also affects the material properties of the virus structure?
Solid state nuclear magnetic resonance
Editor in Chief, Condensates.com
Do you work with a protein found in filaments? If you're interested in getting atomic resolution information on them, this review might give you a push in the right direction.
Physical review letters
Cell
Editor in Chief, Condensates.com
There's a sweet Cell video abstract for this paper! I've saved it to our library of Resources for quick access: https://condensates.com/resources/a-sweet-cell-paperflick-on-new-tools-to-study-phase-separation/
Cell
Editor in Chief, Condensates.com
There's a sweet Cell video abstract for this paper! I've saved it to our library of Resources for quick access: https://condensates.com/resources/a-sweet-cell-paperflick-on-new-tools-to-study-phase-separation/
Journal of molecular biology