bioRxiv
Publications
Most Recent
British journal of pharmacology
Targeting TDP-43 Proteinopathy With Drugs and Drug-Like Small Molecules
Jill Bouchard
Contributing editor, Condensates.com
This review covers how some drugs affect TDP-43 mislocalization.
Scientific reports
Dengue Virus Capsid Protein Dynamics Reveals Spatially Heterogeneous Motion in Live-Infected-Cells
Jill Bouchard
Contributing editor, Condensates.com
It looks like dengue viral capsid phase separates and joins the nucleolus as part of it's invasion strategy... another way (of the many) that viruses use our condensates against us.
Current opinion in cell biology
Karyopherins and Condensates
Trends in biochemical sciences
Mechanisms and Regulation of RNA Condensation in RNP Granule Formation
Experimental cell research
Cellular Stress Orchestrates the Localization of hnRNP H to Stress Granules
Jill Bouchard
Contributing editor, Condensates.com
Many of the hnRNP-family proteins have been shown to localize to stress granules. It looks like the hnRNP H is no different.
The Journal of Biological Chemistry
Phase-separated Condensate-Aided Enrichment of Biomolecular Interactions for High-Throughput Drug Screening in Test Tubes
Molecular Cell
Sequence-Independent Self-Assembly of Germ Granule mRNAs Into Homotypic Clusters
Journal of molecular cell biology
The Protective Role of m1A During Stress-Induced Granulation
Jill Bouchard
Contributing editor, Condensates.com
Here's the second article this week showing a role of mRNA methylation in condensate formation... only this time it's m1A (where the N1 A gets post-transcriptionally modified).
The FEBS journal
The More the Merrier: Effects of Macromolecular Crowding on the Structure and Dynamics of Biological Membranes
Jill Bouchard
Contributing editor, Condensates.com
This review covers 2 types of condensates lipid-droplets and protein-phase separation at and near membranes. Check it out if you'd like to learn about the latest developments.