An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase

Authors Alexander E Conicella   , Rui Huang   , Zev A Ripstein  , Ai Nguyen , Eric Wang , Thomas Löhr , Peter Schuck , Michele Vendruscolo , John L Rubinstein   , Lewis E Kay    
DetailsAlexander E Conicella et al; Proc Natl Acad Sci U S A; 2020;
DOI10.1073/pnas.2013920117
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Jill Bouchard
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Jill Bouchard
Contributing editor, Condensates.com

Here’s a thorough biophysical analysis of an IDP involved in membrane remodeling. I bet the methods would also be useful to study condensate-mediated membrane bending.