Disruption of Cellular Proteostasis by H1N1 Influenza A Virus Causes α-Synuclein Aggregation
| Authors | Rita Marreiros , Andreas Müller-Schiffmann , Svenja V Trossbach , Ingrid Prikulis , Sebastian Hänsch , Stefanie Weidtkamp-Peters , Ana Raquel Moreira , Shriya Sahu , Irina Soloviev , Suganya Selvarajah , Vishwanath R Lingappa , Carsten Korth |
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| Details | Rita Marreiros et al; Proc Natl Acad Sci U S A; 2020 |
| DOI | 10.1073/pnas.1906466117 |
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| Source | View on PubMed |
It’s interesting that viral infection results in the aggregation of α-synuclein, but not of tau or TDP-43. And the anti-influenza drug prevented said aggregation. I bet there are some pearls of wisdom within.