Effect of Alzheimer’s Disease Causative and Protective Mutations on the Hydration Environment of Amyloid- β
Authors | Leena Aggarwal, Parbati Biswas |
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Details | Leena Aggarwal et al; J Phys Chem B; 2020 |
DOI | 10.1021/acs.jpcb.9b10425 |
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Source | View on PubMed |
It looks like the hydration environment gives us insight into why each mutant forms fibrils or doesn’t. I wonder if this method has predictive power for other fibril-forming proteins?