HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains

Authors Ashwanth C Francis , Mariana Marin , Parmit K Singh  , Vasudevan Achuthan  , Mathew J Prellberg , Kristina Palermino-Rowland , Shuiyun Lan , Philip R Tedbury , Stefan G Sarafianos , Alan N Engelman  , Gregory B Melikyan  
DetailsAshwanth C Francis et al; Nat Commun; 2020;
DOI10.1038/s41467-020-17256-8
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Jill Bouchard
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Jill Bouchard
Contributing editor, Condensates.com

It looks like HIV hits nuclear speckles hard in order to get into the host genome.