Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2

Authors Einav Tayeb-Fligelman, Xinyi Cheng, Christen Tai, Jeannette T. Bowler, Sarah Griner, Michael R. Sawaya, Paul M. Seidler, Yi Xiao Jiang, Jiahui Lu, Gregory M. Rosenberg, Lukasz Salwinski, Romany Abskharon, Chih-Te Zee, Ke Hou, Yan Li, David Boyer, Kevin A. Murray, Genesis Falcon, Daniel H. Anderson, Duilio Cascio, Lorena Saelices, Robert Damoiseaux, Feng Guo, David Eisenberg
Details bioRxiv. March 18, 2021
DOI 10.1101/2021.03.05.434000
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Nice–designing peptide inhibitors that target the zipper driving phase separation may be an option for therapeutic intervention.