Inhibition of anti-viral stress granule formation by coronavirus endoribonuclease nsp15 ensures efficient virus replication

Authors Bo Gao , Xiaoqian Gong  , Shouguo Fang , Wenlian Weng , Huan Wang , Hongyan Chu , Yingjie Sun , Chunchun Meng , Lei Tan , Cuiping Song , Xusheng Qiu , Weiwei Liu , Maria Forlenza , Chan Ding  , Ying Liao 
Details Bo Gao et al; PLoS Pathog; 2021;
DOI 10.1371/journal.ppat.1008690
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Jill Bouchard
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Jill Bouchard
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It looks like coronaviruses have a conserved function of shutting down host stress granules in order to replicate effectively.