Intercellular Transmission of a Synthetic Bacterial Cytotoxic Prion-Like Protein in Mammalian Cells

Authors Aida Revilla-García , Cristina Fernández , María Moreno-Del Álamo , Vivian de Los Ríos , Ina M Vorberg , Rafael Giraldo 
Details Aida Revilla-García et al; mBio; 2020;
DOI 10.1128/mBio.02937-19
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Jill Bouchard
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Jill Bouchard
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Intriguing… a bacterial prion-like protein can pass aggregates onto daughter cells, and cause similar effects on mitrochondria as neurodegeneration. Then the authors took it a couple steps further and put it into mammals–read on for all the details.