Nuclear export of chimeric mRNAs depends on an lncRNA-triggered autoregulatory loop in blood malignancies

Authors Zhen-Hua Chen , Tian-Qi Chen , Zhan-Cheng Zeng , Dan Wang , Cai Han , Yu-Meng Sun , Wei Huang , Lin-Yu Sun , Ke Fang , Yue-Qin Chen , Xue-Qun Luo , Wen-Tao Wang 
Details Zhen-Hua Chen et al; Cell Death Dis; 2020;
DOI 10.1038/s41419-020-02795-1
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Jill Bouchard
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Jill Bouchard
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Interesting–an lncRNA “hijacks both the chimeric mRNAs and fusion proteins in nuclear speckles.” Looks like paraspeckles aren’t the only speckle condensate with close ties to lncRNA.