Nucleus Size and DNA Accessibility Are Linked to the Regulation of Paraspeckle Formation in Cellular Differentiation
Authors | Markus Grosch , Sebastian Ittermann , Ejona Rusha , Tobias Greisle , Chaido Ori , Dong-Jiunn Jeffery Truong , Adam C O'Neill , Anna Pertek , Gil Gregor Westmeyer , Micha Drukker |
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Details | Markus Grosch et al; BMC Biol; 2020; |
DOI | 10.1186/s12915-020-00770-y |
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Source | View on PubMed |
It looks like nuclear lncRNA condensates (including paraspeckles) might serve important roles in cellular regulation and may be targeted therapeutically.