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Process optimization and protein engineering mitigated manufacturing challenges of a monoclonal antibody with liquid-liquid phase separation issue by disrupting inter-molecule electrostatic interactions

Authors Du Q, Damschroder M, Pabst TM, Hunter AK, Wang WK, Luo H
Details MAbs. 2019 May/Jun;11(4):789-802. doi: 10.1080/19420862.2019.1599634. Epub 2019 Apr 14
DOI 10.1080/19420862.2019.1599634
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