Quantitative Conformational Analysis of Functionally Important Electrostatic Interactions in the Intrinsically Disordered Region of Delta Subunit of Bacterial RNA Polymerase

Authors Kuban V, Srb P, Stegnerova H, Padrta P, Zachrdla M, Jasenakova Z, Šanderová H, Vítovská D, Krasny L, Koval T, Dohnalek J, Ziemska-Legi Cka J, Grynberg M, Jarnot P, Gruca A, Jensen MR, Blackledge M, Zidek L
Details J Am Chem Soc. 2019 Sep 24. doi: 10.1021/jacs.9b07837
DOI 10.1021/jacs.9b07837
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Jill Bouchard
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Jill Bouchard
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This is an elegant study showing how electrostatic interactions play an important role in RNA polymerase function. I bet they are also important for its localization in condensates.

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January 23, 2020 9:40 am