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RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation

Authors Jordina Guillén-Boixet , Andrii Kopach , Alex S Holehouse , Sina Wittmann , Marcus Jahnel , Raimund Schlüßler , Kyoohyun Kim , Irmela R E A Trussina , Jie Wang , Daniel Mateju , Ina Poser , Shovamayee Maharana , Martine Ruer-Gruß , Doris Richter , Xiaojie Zhang , Young-Tae Chang , Jochen Guck , Alf Honigmann , Julia Mahamid , Anthony A Hyman , Rohit V Pappu , Simon Alberti , Titus M Franzmann 
Details Jordina Guillén-Boixet et al; Cell; 2020;
DOI 10.1016/j.cell.2020.03.049
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Jill Bouchard
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Jill Bouchard
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I like how this work was able to break down RNP condensation to a single protein’s conformational switch.