Sirtuin 6 is required for the integrated stress response and resistance to inhibition of transcriptional cyclin-dependent kinases
| Authors | Nithya Kartha , Jessica E Gianopulos , Zachary Schrank , Sarah M Cavender , Stephanie Dobersch , Bryan D Kynnap , Adrianne Wallace-Povirk , Cynthia L Wladyka , Juan F Santana , Jaeseung C Kim , Angela Yu , Caroline M Bridgwater , Kathrin Fuchs , Sarah Dysinger , Aaron E Lampano , Faiyaz Notta , David H Price , Andrew C Hsieh , Sunil R Hingorani , Sita Kugel |
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| Details | Nithya Kartha et al; Sci Transl Med; 2023; |
| DOI | 10.1126/scitranslmed.abn9674 |
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| Source | View on PubMed |
And nuclear speckles seem to play a role in this process. Read the paper to find out more.