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Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease

Authors Richard J. Wheeler, Hyun O. Lee, Ina Poser, Arun Pal, Thom Doeleman, Satoshi Kishigami, Sukhleen Kour, Eric Nathaniel Anderson, Lara Marrone, Anastasia C. Murthy, Marcus Jahnel, Xiaojie Zhang, Edgar Boczek, Anatol Fritsch, Nicolas L. Fawzi, Jared Sterneckert, Udai Pandey, Della C. David, Benjamin G. Davis, Andrew J. Baldwin, Andreas Hermann, Marc Bickle, Simon Alberti, Anthony A. Hyman
Details bioRxiv. August 21, 2019
DOI 10.1101/721001
Source View on BioRxiv

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Jill Bouchard
Jill Bouchard
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Cool! One step closer to treating ALS by modulating phase behavior.