Suppression of liquid-liquid phase separation by 1,6-hexanediol partially compromises the 3D genome organization in living cells

Authors Sergey V. Ulianov, Artem K. Velichko, Mikhail D. Magnitov, Artem V. Luzhin, Arkadiy K. Golov, Natalia Ovsyannikova, Igor I. Kireev, Alexander V. Tyakht, Alexey A. Gavrilov, Omar L. Kantidze, Sergey V. Razin
DetailsbioRxiv. May 19, 2020
DOI10.1101/2020.05.18.101261
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Jill Bouchard
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Jill Bouchard
Contributing editor, Condensates.com

This study suggests LLPS fine-tunes 3D genome organization.