View Your Favorites

    Access your saved content with one easy click.

    My Favorites

    Save Your Favorites

    Subscribe for free to save your favorites and view a personalized view of content.

    Subscribe for Free

    Be a Contributor

    Submit new content suggestions for Condensates.com.

    Contribute

Targeting intrinsically disordered proteins at the edge of chaos

Authors Ruan H, Sun Q, Zhang W, Liu Y, Lai L
Details Drug Discov Today. 2019 Jan;24(1):217-227. doi: 10.1016/j.drudis.2018.09.017. Epub 2018 Sep 29
DOI 10.1016/j.drudis.2018.09.017
Topics
Tags
Source View on PubMed
Share

Suggested Publications

Biomolecular condensates

Biomolecular Condensates Dictate the Folding Landscape of Protein Alpha-Helices

Biology and Physics of Condensates | Neurology | Technology
Learn More
Biomolecular condensates | Intrinsically disordered proteins | Phase separation

A pH-Responsive fluorescence lifetime probe reveals GOT1 phase separation in cellular anti-senescence

Biology and Physics of Condensates | Biotechnology and engineering | Metabolism
Learn More
Biomolecular condensates | Heterochromatin | Phase separation

Multiscale physical effects of CpG methylation on DNA mechanics, nucleosome wrapping, and chromatin condensates

Biology and Physics of Condensates
Learn More
Biomolecular condensates | Heterochromatin | Phase separation

Intragenomic homologs with distinct phase behaviors broaden the range of cellular stress responses

Biology and Physics of Condensates
Learn More
Biomolecular condensates | Intrinsically disordered proteins | Phase separation

Decitabine suppresses triple-negative breast cancer by disrupting DNMT1 liquid-liquid phase separation and synergizes with G9a inhibition

Biology and Physics of Condensates | Cancer | Drug Discovery
Learn More