TDP-43 α-Helical Structure Tunes Liquid-Liquid Phase Separation and Function

Authors Alexander E Conicella   , Gregory L Dignon  , Gül H Zerze  , Hermann Broder Schmidt , Alexandra M D'Ordine , Young C Kim , Rajat Rohatgi  , Yuna M Ayala , Jeetain Mittal , Nicolas L Fawzi 
DetailsAlexander E Conicella et al; Proc Natl Acad Sci U S A; 2020
DOI10.1073/pnas.1912055117
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Jill Bouchard
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Jill Bouchard
Contributing editor, Condensates.com

Cool stuff: enhancing the helicity of one section in TDP-43 increases function and self-assembly/rigidity of condensates.