TDP-43 α-Helical Structure Tunes Liquid-Liquid Phase Separation and Function
Authors | Alexander E Conicella , Gregory L Dignon , Gül H Zerze , Hermann Broder Schmidt , Alexandra M D'Ordine , Young C Kim , Rajat Rohatgi , Yuna M Ayala , Jeetain Mittal , Nicolas L Fawzi |
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Details | Alexander E Conicella et al; Proc Natl Acad Sci U S A; 2020 |
DOI | 10.1073/pnas.1912055117 |
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Source | View on PubMed |
Cool stuff: enhancing the helicity of one section in TDP-43 increases function and self-assembly/rigidity of condensates.