The juxtamembrane linker of synaptotagmin 1 regulates Ca2+ binding via liquid-liquid phase separation

Authors Nikunj Mehta , Sayantan Mondal , Emma T Watson , Qiang Cui , Edwin R Chapman 
Details Nikunj Mehta et al; Nat Commun; 2024;
DOI 10.1038/s41467-023-44414-5
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This article investigates how the juxtamembrane linker of synaptotagmin 1, a neuronal calcium sensor for exocytosis, regulates its function by mediating liquid-liquid phase separation.