The mutational landscape of a prion-like domain

Authors Bolognesi B,, Faure AJ, Seuma M,, Schmiedel JM, Tartaglia GG,,,, Lehner B,,
Details Nat Commun. 2019 Sep 13;10(1):4162. doi: 10.1038/s41467-019-12101-z
DOI 10.1038/s41467-019-12101-z
Topics
Keywords
Source View on PubMed

1
Join the conversation

Create an Account or Sign In to comment.
1 Comment threads
0 Thread replies
0 Followers
 
Most reacted comment
Hottest comment thread
1 Comment authors
Jill Bouchard Recent comment authors
newest oldest most voted
Jill Bouchard
Admin
Jill Bouchard
Editor in Chief, Condensates.com

This is a very cool use of deep mutational scanning, but the results are quite controversial since they oppose current paradigms in phase separation and aggregation. I’m excited to see where the future goes with these ideas.