The mutational landscape of a prion-like domain
|Authors||Bolognesi B,, Faure AJ, Seuma M,, Schmiedel JM, Tartaglia GG,,,, Lehner B,,|
|Details||Nat Commun. 2019 Sep 13;10(1):4162. doi: 10.1038/s41467-019-12101-z|
|Source||View on PubMed|
This is a very cool use of deep mutational scanning, but the results are quite controversial since they oppose current paradigms in phase separation and aggregation. I’m excited to see where the future goes with these ideas.