TiPARP Forms Nuclear Condensates to Degrade HIF-1α and Suppress Tumorigenesis

Authors Lu Zhang, Ji Cao, Longying Dong, Hening Lin
DetailsLu Zhang; Proc Natl Acad Sci U S A; 2020;
DOI10.1073/pnas.1921815117
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Jill Bouchard
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Jill Bouchard
Contributing editor, Condensates.com

Here is the description of a very elegant feedback loop utilizing phase separation to turn off transcription factors.