+TIPs condense on microtubule plus-ends

Authors Bernardo Gouveia, Sabine Petry
Details Bernardo Gouveia et al; Nat Cell Biol; 2033
DOI 10.1038/s41556-022-01068-7
Source View on PubMed

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Jill Bouchard
Jill Bouchard
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Here’s the News & Views article about the 3 recent papers in Nat Cell Biol showing phase separation is involved in microtubule dynamics. Find each below:
1. Multivalent interactions facilitate motor-dependent protein accumulation at growing microtubule plus-ends
2. Multivalency ensures persistence of a +TIP body at specialized microtubule ends
3. Phase separation of EB1 guides microtubule plus-end dynamics