The authors looked into whether the arrangement of LLPS-promoting and solubilizing sequences in the genome lead to single genome packaging. Read on to learn about generalizable principles of virus compaction.

bioRxiv

Pressure-Jump Kinetics of Liquid-Liquid Phase Separation: Comparison of Two Different Condensed Phases of the RNA-Binding Protein, Fused in Sarcoma

ATP biphasically modulates LLPS of TDP-43 PLD by specifically binding arginine residues

Tau protein liquid-liquid phase separation can initiate tau aggregation

Electrostatically driven complex coacervation and amyloid aggregation of tau are independent processes with overlapping conditions

Is transcriptional regulation just going through a phase?

Molecular determinants for regulation of G3BP1/2 phase separation by the SARS-CoV-2 nucleocapsid protein

Phase separation of Epstein-Barr Virus EBNA2 and Its Coactivator EBNALP controls gene expression

Liquid-liquid phase separation of tau driven by hydrophobic interaction facilitates fibrillization of tau

Role of spatial patterning of N-protein interactions in SARS-CoV-2 genome packaging

Jill Bouchard

Role of spatial patterning of N-protein interactions in SARS-CoV-2 genome packaging

Postdoctoral Biochemist in condensate biology

Sr. Research Associate – Cell Engineering

Scientist/Sr. Scientist – Platform Technology