Frontiers in genetics
bioRxiv
DNA-dependent phase separation by human SSB2 (NABP1/OBFC2A) protein points to adaptations to eukaryotic genome repair processes
bioRxiv
Liquid-liquid Phase Separation of Alpha-synuclein Increases the Structural Variability of Fibrils Formed during Amyloid Aggregation
bioRxiv
Phase partitioning rules Rab domain formation, growth and identity
bioRxiv
DNA-dependent phase separation by human SSB2 (NABP1/OBFC2A) protein points to adaptations to eukaryotic genome repair processes
The Journal of biological chemistry
Formation of biological condensates via phase separation: Characteristics, analytical methods, and physiological implications
Cell
Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization
Cell
Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites
Proceedings of the National Academy of Sciences of the United States of America
Three archetypical classes of macromolecular regulators of protein liquid-liquid phase separation
Jill Bouchard
Editor in Chief, Condensates.com
It's quite common to use molecular crowders to recreate phase separation in vitro. This study gives key insights into the types of interactions each crowder promotes.
Journal of the American Chemical Society
Pressure-Sensitive and Osmolyte-Modulated Liquid-Liquid Phase Separation of Eye-Lens γ-Crystallins
Jill Bouchard
Editor in Chief, Condensates.com
Cool! Deep sea fish have extra osmolytes in their eyes to stabilize their condensates at high pressure, giving them an adaptive advantage! I wonder if these insights could help us treat cataracts?