May

30

Condensate Colloquium Series: Margaret Gardel & Konstanze Winkloher — May 30

Tuesday, May 30, 2023

Must Read

Nature chemistry

Fibril formation and ordering of disordered FUS LC driven by hydrophobic interactions

The journal of physical chemistry B

Crosslink-Induced Conformation Change of Intrinsically Disordered Proteins Have a Nontrivial Effect on Phase Separation Dynamics and Thermodynamics

Neurobiology of disease

Liquid – liquid phase separation of tau: Driving forces, regulation, and biological implications

Nature communications

Wetting and complex remodeling of membranes by biomolecular condensates

Nature structural & molecular biology

Intrinsic mesoscale properties of a Polycomb protein underpin heterochromatin fidelity

Biophysical journal

What’s past is prologue: FRAP keeps delivering 50 years later

Nucleus (Austin, Tex)

Transcriptional condensates and phase separation: condensing information across scales and mechanisms

Cell reports

Cellular uptake of nickel by NikR is regulated by phase separation

bioRxiv

Micelle-like clusters in phase-separated Nanog condensates: A molecular simulation study

Methods in molecular biology (Clifton, NJ)

Quantitative Analysis of PcG-Associated Condensates by Stochastic Optical Reconstruction Microscopy (STORM)

Research (Washington, DC)

Phosphorylation Promotes the Accumulation of PERIOD Protein Foci

Journal of molecular biology

Molten globule driven and self-downmodulated phase separation of a viral factory scaffold

Current opinion in chemical biology

Towards sequence-based principles for protein phase separation predictions

Research (Washington, DC)

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage

The Plant cell

Cajal bodies: Evolutionarily conserved nuclear biomolecular condensates with properties unique to plants

Jun

21

Jonathan O’Connell on High Throughput Screening in Drug Discovery

Wednesday, June 21, 2023