Frontiers in Molecular Biosciences Research Topic on The Role of Protein Post-Translational Modifications in Protein-RNA Interactions and RNP Assemblies

Frontiers in molecular biosciences

Editorial: The Role of Protein Post-Translational Modifications in Protein-RNA Interactions and RNP Assemblies

• Neurodegeneration
• Phase Separation
• Physics of Condensates
• Transcription

Jill Bouchard

Editor in Chief, Condensates.com

Here's the Editorial introducing the Frontiers in Molecular Biosciences' Research Topic on The Role of Protein Post-Translational Modifications in Protein-RNA Interactions and RNP Assemblies. Check out all the associated papers with the FrontMolBiosci tag.

Phosphorylation Regulates CIRBP Arginine Methylation, Transportin-1 Binding and Liquid-Liquid Phase Separation

• Metabolism
• Methods
• Neurodegeneration
• Phase Separation
• Physics of Condensates
• Transcription

Frontiers In Molecular Biosciences

Systematic Analysis of the Impact of R-Methylation on RBPs-RNA Interactions: A Proteomic Approach

• Methods
• Phase Separation
• Physics of Condensates

Frontiers in molecular biosciences

Post-Translational Modifications Modulate Proteinopathies of TDP-43, FUS and hnRNP-A/B in Amyotrophic Lateral Sclerosis

• Neurodegeneration
• Phase Separation
• Physics of Condensates

Frontiers In Molecular Biosciences

Arginine Methyltransferases as Regulators of RNA-Binding Protein Activities in Pathogenic Kinetoplastids

• Phase Separation
• Transcription

Frontiers In Molecular Biosciences

Opportunities and Challenges in Global Quantification of RNA-Protein Interaction via UV Cross-Linking

• Methods
• Phase Separation

Frontiers in molecular biosciences

SUMO: Glue or Solvent for Phase-Separated Ribonucleoprotein Complexes and Molecular Condensates?

• Cancer
• Infectious Disease
• Neurodegeneration
• Phase Separation

Frontiers in molecular biosciences

Post-translational Control of RNA-Binding Proteins and Disease-Related Dysregulation

• Metabolism
• Neurodegeneration
• Phase Separation

Jill Bouchard

Editor in Chief, Condensates.com

It's not surprising that phase separation gets quite a bit of discussion throughout this review.

Frontiers in Molecular Biosciences

A Comprehensive Analysis of the Role of hnRNP A1 Function and Dysfunction in the Pathogenesis of Neurodegenerative Disease

• Cancer
• Metabolism
• Neurodegeneration
• Phase Separation
• Transcription

Jill Bouchard

Editor in Chief, Condensates.com

This review covers the biophysical behavior of the prion-like domain of hnRNPA1 and how it drives phase separation.

Frontiers in Molecular Biosciences

An Emerging Role for Post-translational Modifications in Regulating RNP Condensates in the Germ Line

• Neurodegeneration
• Phase Separation
• Physics of Condensates