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Carlos Castañeda on Ubiquitin-Mediated Phase Transitions in Protein Quality Control
Wednesday, April 28, 2021
The journal of physical chemistry B
Biophysics of Phase Separation of Disordered Proteins Is Governed by Balance between Short- And Long-Range Interactions
Nature chemical biology
ROS regulated reversible protein phase separation synchronizes plant flowering
IDPSeminars: Malene Ringkjøbing Jensen & Ylva Ivarsson — Mar 4
Thursday, March 4, 2021
Proteostasis Consortium: Rohit Pappu
Wednesday, March 10, 2021
IDPSIG and friends Virtual Symposium
Thursday, March 11, 2021
bioRxiv
Cyclophilin A regulates protein phase separation and mitigates haematopoietic stem cell aging
bioRxiv
Previously uncharacterized interactions between the folded and intrinsically disordered domains impart asymmetric effects on UBQLN2 phase separation
iScience
Characterization of functional disordered regions within chromatin-associated proteins
Jill Bouchard
Contributing editor, Condensates.com
And one of the functions this review focuses on is phase separation.
Biophysical journal
Physical modelling of multivalent interactions in the nuclear pore complex
Current opinion in cell biology
Nucleocytoplasmic partitioning as a mechanism to regulate Arabidopsis signaling events
Jill Bouchard
Contributing editor, Condensates.com
This review covers the role condensates play in regulating transcription in plants.
Methods (San Diego, Calif)
Single-molecule and ensemble methods to probe RNP nucleation and condensate properties
Genomics, proteomics & bioinformatics
Computational Screening of Biological Phase-separating Proteins
Molecular cell
Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation
Bioconjugate chemistry
Peptide Assemblies Mimicking Chaperones for Protein Trafficking
bioRxiv
Pak1 kinase regulates ribonucleoprotein granules through Sts5 for polarized growth and the glucose starvation response
Jill Bouchard
Contributing editor, Condensates.com
Here's an interesting study showing the effects of phosphorylation on an IDP's ability to localize with P bodies.
Journal of chemical information and modeling
Recent Force Field Strategies for Intrinsically Disordered Proteins
bioRxiv
The cohesin regulator Stag1 promotes cell plasticity through heterochromatin regulation
Jill Bouchard
Contributing editor, Condensates.com
It looks like this paper has identified a new regulator of certain condensates, with big implications for disease too.
Nature communications