Dec
14
VIB Online Course on Liquid-Liquid Phase Separation
Monday, December 14, 2020
Most Recent
Molecular cell
Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis
bioRxiv
Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins
Frontiers in oncology
Metabolic Compartmentalization at the Leading Edge of Metastatic Cancer Cells
Biomaterials Science
Thermostabilization of viruses via complex coacervation
bioRxiv
Ligand Effects on Phase Separation of Multivalent Macromolecules
Nature
Assembly of synaptic active zones requires phase separation of scaffold molecules
Dec
10
The Protein Society Webinar #5: Liquid-liquid Phase Separation (LLPS) of Proteins and Their Role in Pathology
Thursday, December 10, 2020
Cell cycle (Georgetown, Tex)
Phase separation of the Cep63•Cep152 complex underlies the formation of dynamic supramolecular self-assemblies at human centrosomes
Nature medicine
Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs
Methods in molecular biology (Clifton, NJ)
Monitoring Acetylation of the RNA Helicase DDX3X, a Protein Critical for Formation of Stress Granules
Jill Bouchard
Contributing editor, Condensates.com
These authors had a pretty stellar Nat Chem Biol paper showing how acetylation regulates phase separation last year. Now they're sharing their protocol--check it out!
The EMBO journal
SARS-CoV-2 nucleocapsid protein phase-separates with RNA and with human hnRNPs
bioRxiv
Design of intrinsically disordered proteins that undergo phase transitions with lower critical solution temperatures
Nereid Therapeutics Launches: ATP $50M Series A NewCo Co-Founded with Brangwynne, Pioneer of Biomolecular Condensates Field
Molecular cell
Vesicle Tethering on the Surface of Phase-Separated Active Zone Condensates
Cells
Divide and Rule: Phase Separation in Eukaryotic Genome Functioning
Biophysical journal
The Emergence of Phase Separation as an Organizing Principle in Bacteria
Virology
Cauliflower mosaic virus P6 inclusion body formation: A dynamic and intricate process
Jill Bouchard
Contributing editor, Condensates.com
If it looks like a duck and quacks like a duck, it's probably a... condensate! haha :) Well I really meant if it looks like a blob and fuses...
Molecular cell
A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits
bioRxiv