Most Recent
bioRxiv
Capillary forces drive pioneer transcription factor-mediated DNA condensation
International journal of molecular sciences
Protein Databases Related to Liquid-Liquid Phase Separation
PhD in statistical physics modeling of intracellular condensates
EPFL - Ecole Polytechnique Federale de Lausanne | Lausanne, Switzerland
ApplyMolecular & cellular oncology
Dual role of PRMT1-dependent arginine methylation in cellular responses to genotoxic stress
bioRxiv
Phase Separation Can Increase Enzyme Activity by Concentration and Molecular Organization
The journal of physical chemistry B
Unraveling Molecular Interactions in Liquid-Liquid Phase-Separation of Disordered Proteins by Atomistic Simulations
FEBS open bio
Dissecting the transactivation domain (tAD) of the transcription factor c-Myb to assess recent models of tAD function
Jill Bouchard
Contributing editor, Condensates.com
Here's a nice study testing the contribution of Short LInear Motif (SLIM) exposure vs LLPS. Intriguingly, the authors found SLIMs dominate in 2 mammalian systems, yet LLPS dominated in yeast.
PhD student
Wageningen University | Wageningen, Netherlands
ApplyPostdoc positions at University of California – San Francisco
UCSF | San Francisco, CA
ApplyNature cell biology
Nucleated transcriptional condensates amplify gene expression
Postdoctoral Associate, Physics
University at Buffalo | Buffalo, New York
ApplyBioRxiv
FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation
bioRxiv
Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation
Jill Bouchard
Contributing editor, Condensates.com
And those fuzzy interactions also contribute to phase separation at or near the membrane--pretty cool stuff!
Nature Communications
Tunable multiphase dynamics of arginine and lysine liquid condensates
bioRxiv
High fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate
bioRxiv
SARS CoV-2 nucleocapsid protein forms condensates with viral genomic RNA
Sep
16
Max Planck Schools–Matter to Life Lecture Series: Anthony Hyman
Wednesday, September 16, 2020
Soft matter
Synchronized fractionation and phase separation in binary colloids
Jill Bouchard
Contributing editor, Condensates.com
Here's some interesting physics about the forces underlying the formation of gels, liquids and crystals, with implications for how reversible condensates form in cells.
Macromolecules
Nonionic Block Copolymer Coacervates
Aoon Rizvi
PhD Candidate, UC Irvine
This is one of the first examples of nonionic block copolymers used to form coacervates and manipulate them to create materials over multiple length scales! In-situ TEM also allowed to image the coacervate formation at the nano-scale which supplemented the proposed mechanism of the final self-assembled structures. The condensate community looking for simple and easily synthesized polymers to form coacervate based material should find this interesting!