bioRxiv
Most Recent
Proteins
Influence of ALS-linked M337V mutation on the conformational ensembles of TDP-43321-340 peptide monomer and dimer
Feb
28
Condensate Colloquium Series: Dylan Murray & Karsten Rippe — Feb 28
Tuesday, February 28, 2023
Kitchen Table Talk
Must ReadVIDEO: Dorothee Dormann on Aberrant Phase Transitions of Neurodegeneration-Linked RNA-Binding Proteins: control mechanisms and functional consequences
Chemical science
Thermodynamic origins of two-component multiphase condensates of proteins
bioRxiv
Pervasive, conserved secondary structure in highly charged protein regions
Jill Bouchard
Editor in Chief, Condensates.com
Interesting--according to this work, many highly charged protein regions that are thought to be disordered actually end up being helical. This may have important implications for proteins thought to be involved in condensates.
The journal of physical chemistry letters
Nucleation of Biomolecular Condensates from Finite-Sized Simulations
Nature communications
VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid-liquid phase separation
Trends in biochemical sciences
Interaction modules that impart specificity to disordered protein
Proceedings of the National Academy of Sciences of the United States of America
CPEB3 low-complexity motif regulates local protein synthesis via protein-protein interactions in neuronal ribonucleoprotein granules
bioRxiv
Single fluorogen imaging reveals spatial inhomogeneities within biomolecular condensates
JACS Au
Sequence Tendency for the Interaction between Low-Complexity Intrinsically Disordered Proteins
Genome biology
The mechanism underlying redundant functions of the YTHDF proteins
Journal of the American Chemical Society
Liquid Droplet Aging and Seeded Fibril Formation of the Cytotoxic Granule Associated RNA Binding Protein TIA1 Low Complexity Domain
bioRxiv
Odd-even disparity in the population of slipped hairpins in RNA repeat sequences with implications for phase separation
Jan
10
Condensate Colloquium Series: Shasha Chong & Samuel Safran — Jan 10
Tuesday, January 10, 2023
Journal of biochemistry
Classification of proteins inducing liquid-liquid phase separation: sequential, structural and functional characterization
Proceedings of the National Academy of Sciences of the United States of America
Inhibiting androgen receptor splice variants with cysteine-selective irreversible covalent inhibitors to treat prostate cancer
bioRxiv
Reordering of aromatic-rich segments in FUS inhibits ageing of FUS-RNA condensates
Nature communications