Plant cell reports
Most Recent
Protein science : a publication of the Protein Society
Fused in sarcoma undergoes cold denaturation: Implications for phase separation
Epigenomes
Regulation of Polyhomeotic Condensates by Intrinsically Disordered Sequences That Affect Chromatin Binding
Essays in biochemistry
Shapeshifting tau: from intrinsically disordered to paired-helical filaments
bioRxiv
Nucleation of Biomolecular Condensates from Finite-Sized Simulations
bioRxiv
Interplay of the folded domain and disordered low-complexity domains along with RNA sequence mediate efficient binding of FUS with RNA
bioRxiv
Optimizing the Martini 3 force field reveals the effects of the intricate balance between protein-water interaction strength and salt concentration on biomolecular condensate formation
Bioinformatics
The LCD-Composer webserver: high-specificity identification and functional analysis of low-complexity domains in proteins
Sean Cascarina
, Colorado State University
This article describes a webserver that was recently developed to identify low-complexity domains in whole proteomes. The webserver allows researchers to perform customized searches for specific types of low-complexity domains based on predetermined compositional features of the desired low-complexity sequences. Since low-complexity domains have been implicated in condensate formation and regulation, this tool may be of use to those in the condensate community.
Methods in molecular biology (Clifton, NJ)
Biophysical Studies of LLPS and Aggregation of TDP-43 LCD
Biomolecules
Functional Tuning of Intrinsically Disordered Regions in Human Proteins by Composition Bias
Array
Must ReadVIDEO: Alex Holehouse on A Computational Ecosystem for Exploring Disordered Proteins and Condensates
bioRxiv
Regulation of Polyhomeotic condensates by intrinsically disordered sequences that affect chromatin binding
Current biology : CB
Condensation of the fusion focus by the intrinsically disordered region of the formin Fus1 is essential for cell-cell fusion
Experimental & molecular medicine
Phase separation of low-complexity domains in cellular function and disease
eLife
A unified view of low complexity regions (LCRs) across species
Biology
Regulating Phase Transition in Neurodegenerative Diseases by Nuclear Import Receptors
Frontiers in genetics
LncRNAs divide and rule: The master regulators of phase separation
Biomolecules
Low Complexity Induces Structure in Protein Regions Predicted as Intrinsically Disordered
Nov
17
Biomolecular Condensates in Cancer
Thursday, November 17, 2022 | Rancho Santa Fe, CA, United States
Science advances