Science
Most Recent
BioRxiv
Artificial intelligence reveals nuclear pore complexity
Mar
08
CECAM: From disordered biomolecular complexes to biological coacervates
Tuesday, March 8, 2022 | Zurich, Switzerland
BioRxiv
MLF2 modulates phase separated nuclear envelope condensates that provoke dual proteotoxicity
bioRxiv
Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo
Cells
Formation of Non-Nucleoplasmic Proteasome Foci during the Late Stage of Hyperosmotic Stress
Jill Bouchard
Managing editor, Condensates.com
It looks like proteasome foci may be another condensate responsible for stress tolerance in cells.
Kitchen Table Talk
Must ReadVIDEO: Broder Schmidt on Targeting Intrinsically Disordered Proteins (IDPs): In the Pack vs. the Lone Wolf
Nov
01
ONLINE–Cell Symposia: Biological Assemblies: Phase Transitions and More
Monday, November 1, 2021
Chemical reviews
Integration of Mass Spectrometry Data for Structural Biology
Jill Bouchard
Managing editor, Condensates.com
Check out this review to see how complementary methods have been used successfully to characterize fuzzy complexes, including the nuclear pore complex.
Cells
New Activities of the Nuclear Pore Complexes
Jill Bouchard
Managing editor, Condensates.com
Here's the intro to a special issue on the "Nuclear Pore Complex in Nanomedicine". Check it out to find out about some of the new players in the NPC world.
bioRxiv
Desolvation Energy Explains Partitioning of Client Proteins into Condensates
BioRxiv
Crowding-induced phase separation of nuclear transport receptors in FG nucleoporin assemblies
Frontiers in cell and developmental biology
New Family Members of FG Repeat Proteins and Their Unexplored Roles During Phase Separation
Biophysical journal
FG Nucleoporins feature unique amino acid sequence patterns that distinguish them from other IDPs
Jill Bouchard
Managing editor, Condensates.com
I'm betting these unique features of FG Nups has a huge impact on their phase behavior.
Journal of biochemistry
Karyopherin-βs play a key role as a phase separation regulator
Nature Communications
Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide
Analytical and bioanalytical chemistry
Synthetic hydrogel mimics of the nuclear pore complex for the study of nucleocytoplasmic transport defects in C9orf72 ALS/FTD
Trends in cell biology
Chromatin mobility and relocation in DNA repair
Molecular Cell
Co-translational assembly and localized translation of nucleoporins in nuclear pore complex biogenesis
Angewandte Chemie (International ed in English)