Biophysical journal
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Current opinion in cell biology
Nucleocytoplasmic partitioning as a mechanism to regulate Arabidopsis signaling events
Jill Bouchard
Contributing editor, Condensates.com
This review covers the role condensates play in regulating transcription in plants.
Cells
Limited Proteolysis-Coupled Mass Spectrometry Identifies Phosphatidylinositol 4,5-Bisphosphate Effectors in Human Nuclear Proteome
Jill Bouchard
Contributing editor, Condensates.com
Do lipids make it into condensates? This method seeks to uncover the complicated relationship between lipids and many proteins that localize to condensates.
Biochemical Society transactions
Multifunctionality of F-rich nucleoporins
Jill Bouchard
Contributing editor, Condensates.com
I wonder if the difference in localization is due to subtle differences in phase separation propensity and/or material properties? Read on to find out.
Cell reports
Redox-Sensitive Cysteines Confer Proximal Control of the Molecular Crowding Barrier in the Nuclear Pore
Jill Bouchard
Contributing editor, Condensates.com
Based on their results, the authors propose a "model of proximal control of phase separation." Check out the full paper for the details.
Protein science : a publication of the Protein Society
Biomolecular phase separation through the lens of sodium-23 NMR
The EMBO journal
Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages
Jill Bouchard
Contributing editor, Condensates.com
It looks like the condensates in infected macrophages get all messed up. Check out this paper to find out more.
Cell Reports
Acute Heat Stress Leads to Reversible Aggregation of Nuclear Proteins into Nucleolar Rings in Fission Yeast
Nucleic acids research
TPR is required for the efficient nuclear export of mRNAs and lncRNAs from short and intron-poor genes
Jill Bouchard
Contributing editor, Condensates.com
Here's a paper about a protein that facilitates crosstalk between the nuclear pore and nuclear speckles.
The Journal of biological chemistry
Functions of Gle1 are governed by two distinct modes of self-association
Jill Bouchard
Contributing editor, Condensates.com
Here's some mechanistic details about a regulator of stress granules. And the authors speculate its oligomerization may provide a scaffold for them.
Nature
In-cell architecture of the nuclear pore and snapshots of its turnover
Jill Bouchard
Contributing editor, Condensates.com
Is your favorite condensate the NPC? If so, here's a treat for you. If not, this study highlights some methods that could be very helpful to study the structure-function relationships within other condensates.
Biochimica et biophysica acta Molecular basis of disease
Hypusination of Eif5a regulates cytoplasmic TDP-43 aggregation and accumulation in a stress-induced cellular model
Jill Bouchard
Contributing editor, Condensates.com
ICYMI, hypusine is an uncommon PTM on lysine, which causes interesting interactions between this translation initiation factor and proteins involved in 2 condensates (both stress granules and the nuclear pore complex).
The EMBO Journal
Spatial control of nucleoporin condensation by fragile X-related proteins
Developmental cell
Phase Separation in Membrane Biology: The Interplay between Membrane-Bound Organelles and Membraneless Condensates
Trends in biochemical sciences
Biomolecular Condensates in the Nucleus
Jill Bouchard
Contributing editor, Condensates.com
Need an update on what's new with nuclear condensates? This will be a good place to start!
Nature communications
HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains
Jill Bouchard
Contributing editor, Condensates.com
It looks like HIV hits nuclear speckles hard in order to get into the host genome.
Biomaterials
Spatiotemporally Tracking of Nano-Biofilaments Inside the Nuclear Pore Complex Core
Current opinion in cell biology
Karyopherins and Condensates
Kitchen Table Talk
Liam Holt on Crowding and Compression
Emerging topics in life sciences