Genes
Leukocyte Nucleolus and Anisakis pegreffii-When Falling Apart Means Falling in Place
Jill Bouchard
Contributing editor, Condensates.com
Here's a close look at how nucleoli restructure under parasitic attack.
Most Recent
Journal of experimental botany
Tiding-up the Plant Nuclear Space: Domains, Function and Dynamics
Jill Bouchard
Contributing editor, Condensates.com
Here's a review on how condensates play a role in organizing plant chromatin.
Molecular neurodegeneration
Divergence, Convergence, and Therapeutic Implications: A Cell Biology Perspective of C9ORF72-ALS/FTD
Jill Bouchard
Contributing editor, Condensates.com
Here's a nice review integrating all the recent advancements in neurodegeneration studies (including how condensates play a role).
Scientific reports
Dengue Virus Capsid Protein Dynamics Reveals Spatially Heterogeneous Motion in Live-Infected-Cells
Jill Bouchard
Contributing editor, Condensates.com
It looks like dengue viral capsid phase separates and joins the nucleolus as part of it's invasion strategy... another way (of the many) that viruses use our condensates against us.
BioRxiv
Nuclear phosphatidylinositol 3,4,5-trisphosphate interactome uncovers an enrichment in nucleolar proteins
Jill Bouchard
Contributing editor, Condensates.com
It's cool to see important lipid signaling molecules show up in condensates!
Nature Methods
Cell Biology Befriends Soft Matter Physics
Scientific reports
Comparative Analysis of MACROD1, MACROD2 and TARG1 Expression, Localisation and Interactome
Jill Bouchard
Contributing editor, Condensates.com
These proteins appear to be important regulators of nucleoli and stress granules.
3 funded PhD positions on the Role of phase separation mechanisms in higher-order chromatin organization during development
Université de Montpellier | Montpellier, France
ApplyNature
Composition-dependent Thermodynamics of Intracellular Phase Separation
Cells
Super-Resolution Localisation of Nuclear PI(4)P and Identification of Its Interacting Proteome
Jill Bouchard
Contributing editor, Condensates.com
Who knew that lipids made it into nuclear condensates?!
bioRxiv
Mitochondrial cytochrome c liberates the nucleophosmin-sequestered ARF tumor suppressor in the nucleolus
Jill Bouchard
Contributing editor, Condensates.com
This paper shows an interesting cross-talk between the mitochondria and nucleolus upon DNA damage.
Scientific Reports
Super-resolution in Situ Analysis of Active Ribosomal DNA Chromatin Organization in the Nucleolus
Jill Bouchard
Contributing editor, Condensates.com
The architecture of nucleoli is fascinating, and we'll get so many more insights into how they work as more awesome methods like this come out.
Kitchen Table Talk
Priya Banerjee on Phase Transition and Hollow Condensates
Journal of molecular biology
Subcompartment Formation by Phase Separation
Kitchen Table Talk
Tatjana Trcek on Germ Granule mRNA Self-Assembly
BioRxiv
A role for the autophagic receptor, SQSTM1/p62, in trafficking NF-κB/RelA to nucleolar aggresomes
Jill Bouchard
Contributing editor, Condensates.com
Cool! This paper looks into what regulates the sequestration of certain proteins to the nucleolus so it can be exploited to treat cancer.
Tanaffos
New Insights Into Connection of Nucleolar Functions and Cancer
BioRxiv
SPIN reveals genome-wide landscape of nuclear compartmentalization
bioRxiv
Regulation of gene expression by repression condensates during development
Cells