BioRxiv
Most Recent
Tiny liquid droplets are driving a cell biology rethink
Cells
Divide and Rule: Phase Separation in Eukaryotic Genome Functioning
Cell biochemistry and function
Novel nucleolar localization of clusterin and its associated functions in human oral cancers: An in vitro and in silico analysis
Jill Bouchard
Contributing editor, Condensates.com
This paper is about some complex communication between nucleoli and cajal bodies in cancer cells. Check it out to find out more.
Human Frontier Science Program awards Anthony Hyman and Clifford Brangwynne the 2021 HFSP Nakasone Award
Nov
05
IDPSeminars: Aurelia Ball & Richard Kriwacki — Nov 5
Thursday, November 5, 2020
Frontiers in aging neuroscience
Molecular Chaperones: A Double-Edged Sword in Neurodegenerative Diseases
Jill Bouchard
Contributing editor, Condensates.com
This review covers the evidence that molecular chaperones are recruited to certain condensates to help preserve the correct material properties for proper function.
Briefings in bioinformatics
MloDisDB: a manually curated database of the relations between membraneless organelles and diseases
Jill Bouchard
Contributing editor, Condensates.com
Do you want to know what disease(s) your favorite protein or condensate is associated with? You can use this online platform to find out.I’ve saved it in our library of Resources–check it out here: https://condensates.com/resources/mlodisdb/
PhD position in evaluation of liquid-liquid phase separation in disease cells and in vitro using fluorescence lifetime imaging and image correlation spectroscopy
The University of Manchester | Manchester, United Kingdom
ApplyBiophysical Journal
The relative densities of cytoplasm and nuclear compartments are robust against strong perturbation
Science Advances
Transcriptional suppression of ribosomal DNA with phase separation
Biophysical Journal
The relative densities of cytoplasm and nuclear compartments are robust against strong perturbation
Jan
27
Biomolecular Condensates in Cancer
Thursday, January 27, 2022 | Pacific Grove, CA, United States
Developmental cell
Emerging Roles for Phase Separation in Plants
Biology open
Molecular determinants that govern scaRNA processing by Drosha/DGCR8
Jill Bouchard
Contributing editor, Condensates.com
Interesting, it looks like there may be some cross talk between Cajal bodies and nucleoli via scaRNAs.
Biomolecules
Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation
Jill Bouchard
Contributing editor, Condensates.com
Here's some work testing the hypothesis that stress granules and/or P bodies affect TDP-43 aggregation.
Proceedings of the National Academy of Sciences of the United States of America
A mouse tissue atlas of small noncoding RNA
Jill Bouchard
Contributing editor, Condensates.com
Here's a comprehensive analysis of condensate-specific noncoding RNAs from various tissues.
bioRxiv
Capillary forces drive pioneer transcription factor-mediated DNA condensation
Viruses
Functional Characterization of Pepper Vein Banding Virus-Encoded Proteins and Their Interactions: Implications in Potyvirus Infection
Jill Bouchard
Contributing editor, Condensates.com
Here's an interesting review about how a plant virus uses its IDPs for multiple functions... including helping them localize to various membraneless organelles.
bioRxiv