Nature reviews Molecular cell biology
Most Recent
Frontiers in cellular neuroscience
TDP-43 and NEAT long non-coding RNA: Roles in neurodegenerative disease
EMBO reports
Paraspeckles interact with SWI/SNF subunit ARID1B to regulate transcription and splicing
The Journal of biological chemistry
Paraspeckle subnuclear bodies depend on dynamic heterodimerisation of DBHS RNA-binding proteins via their structured domains
bioRxiv
Landscape of semi-extractable RNAs across five human cell lines
bioRxiv
Remarkable improvement in detection of readthrough downstream-of-gene transcripts by semi-extractable RNA-sequencing
Frontiers in molecular biosciences
Keeping up with the condensates: The retention, gain, and loss of nuclear membrane-less organelles
Cancers
The Long and the Short of It: NEAT1 and Cancer Cell Metabolism
Nucleic acids research
A toolkit for the identification of NEAT1_2/paraspeckle modulators
Frontiers in molecular biosciences
Micellization: A new principle in the formation of biomolecular condensates
Haematologica
Activation of lncRNA NEAT1 leads to survival advantage of multiple myeloma cells by supporting a positive regulatory loop with DNA repair proteins
Jill Bouchard
Editor in Chief, Condensates.com
The authors speculate that their results suggest paraspeckles may be a good therapeutic target for Multiple Myeloma.
Frontiers in molecular biosciences
Triblock copolymer micelle model of spherical paraspeckles
Cancers
Molecular Interactions of the Long Noncoding RNA NEAT1 in Cancer
Jill Bouchard
Editor in Chief, Condensates.com
This review has a nice section on the structure of paraspeckles.
Cell death & disease
DNA damage-induced paraspeckle formation enhances DNA repair and tumor radioresistance by recruiting ribosomal protein P0
The EMBO journal
AATF/Che-1 localizes to paraspeckles and suppresses R-loops accumulation and interferon activation in Multiple Myeloma
Computational and structural biotechnology journal
Chromatin Hubs: A biological and computational outlook
Jill Bouchard
Editor in Chief, Condensates.com
This is a really nice review that covers all the ways many condensates are involved in chromatin hubs and transcription. Plus it lists a bunch of methods that may be helpful to investigate this relationship further!
Cell reports
Hyperosmotic-stress-induced liquid-liquid phase separation of ALS-related proteins in the nucleus
Cells
Regulation of Cellular Ribonucleoprotein Granules: From Assembly to Degradation via Post-translational Modification
Methods in molecular biology (Clifton, NJ)
Statistical Thermodynamics Approach for Intracellular Phase Separation
Frontiers in molecular biosciences