Molecular therapy : the journal of the American Society of Gene Therapy
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Nature communications
VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid-liquid phase separation
Communications biology
Confined environments induce polarized paraspeckle condensates
Ageing research reviews
lncRNA NEAT1: key player in neurodegenerative diseases
Frontiers in molecular biosciences
Editorial: The why of RNA granules: Form, function, and regulation
eLife
Long non-coding RNA Neat1 and paraspeckle components are translational regulators in hypoxia
International journal of molecular sciences
The Involvement of Long Non-Coding RNAs in Glutamine-Metabolic Reprogramming and Therapeutic Resistance in Cancer
Cancer informatics
Single-Cell Transcriptome Analysis Reveals Paraspeckles Expression in Osteosarcoma Tissues
bioRxiv
Different low-complexity regions of SFPQ play distinct roles in the formation of biomolecular condensates
Nature reviews Molecular cell biology
A guide to membraneless organelles and their various roles in gene regulation
Frontiers in cellular neuroscience
TDP-43 and NEAT long non-coding RNA: Roles in neurodegenerative disease
EMBO reports
Paraspeckles interact with SWI/SNF subunit ARID1B to regulate transcription and splicing
The Journal of biological chemistry
Paraspeckle subnuclear bodies depend on dynamic heterodimerisation of DBHS RNA-binding proteins via their structured domains
bioRxiv
Landscape of semi-extractable RNAs across five human cell lines
bioRxiv
Remarkable improvement in detection of readthrough downstream-of-gene transcripts by semi-extractable RNA-sequencing
Frontiers in molecular biosciences
Keeping up with the condensates: The retention, gain, and loss of nuclear membrane-less organelles
Cancers
The Long and the Short of It: NEAT1 and Cancer Cell Metabolism
Nucleic acids research
A toolkit for the identification of NEAT1_2/paraspeckle modulators
Frontiers in molecular biosciences
Micellization: A new principle in the formation of biomolecular condensates
Haematologica
Activation of lncRNA NEAT1 leads to survival advantage of multiple myeloma cells by supporting a positive regulatory loop with DNA repair proteins
Jill Bouchard
Editor in Chief, Condensates.com
The authors speculate that their results suggest paraspeckles may be a good therapeutic target for Multiple Myeloma.