bioRxiv
Most Recent
Physical chemistry chemical physics : PCCP
Hydration makes a difference! How to tune protein complexes between liquid-liquid and liquid-solid phase separation
The Journal of biological chemistry
Arg177 and Asp159 from dog prion protein slow liquid-liquid phase separation and inhibit amyloid formation of human prion protein
Biomolecules
The Properties and Domain Requirements for Phase Separation of the Sup35 Prion Protein In Vivo
Frontiers in bioscience (Landmark edition)
Protein Condensates and Protein Aggregates: In Vitro, in the Cell, and In Silico
Frontiers in molecular biosciences
Self-assembling and pH-responsive protein nanoparticle as potential platform for targeted tumor therapy
PLoS Pathogens
Understanding the link between the actin cytoskeleton and prion biology
bioRxiv
Copper drives prion protein phase separation and modulates aggregation
PloS one
TFIID dependency of steady-state mRNA transcription altered epigenetically by simultaneous functional loss of Taf1 and Spt3 is Hsp104-dependent
bioRxiv
Excess PrPC inhibits muscle cell differentiation via miRNA-enhanced liquid–liquid phase separation implicated in myopathy
Methods in molecular biology (Clifton, NJ)
In Vitro Characterization of Protein:Nucleic Acid Liquid-Liquid Phase Separation by Microscopy Methods and Nanoparticle Tracking Analysis
IDPSeminars: Ioana M. Ilie & Jeremy Schmit — September 1
Thursday, September 1, 2022
Current opinion in structural biology
Nucleic acid actions on abnormal protein aggregation, phase transitions and phase separation
Journal of molecular biology
Prion Protein Biology Through the Lens of Liquid-Liquid Phase Separation
Proceedings of the National Academy of Sciences of the United States of America
An intrinsically disordered pathological prion variant Y145Stop converts into self-seeding amyloids via liquid-liquid phase separation
bioRxiv
Spatiotemporal Modulations in Heterotypic Condensates of Prion and α-Synuclein Control Phase Transitions and Amyloid Conversion
Biomolecules
Prion-Like Proteins in Phase Separation and Their Link to Disease
The Journal of biological chemistry
The N-terminal domain of the prion protein is required and sufficient for liquid-liquid phase separation; a crucial role of the Aβ-binding domain
Journal of Physical Chemistry Letters
Ultrasensitive Characterization of the Prion Protein by Surface-Enhanced Raman Scattering: Selective Enhancement via Electrostatic Tethering of the Intrinsically Disordered Domain with Functionalized Silver Nanoparticles
Jill Bouchard
Editor in Chief, Condensates.com
Here's a new way to look at the dilute phase of your favorite phase separating IDP.
The Journal of biological chemistry