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bioRxiv
Phase separation and molecular ordering of the prion-like domain of the thermosensory protein EARLY FLOWERING 3
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
Tau, RNA, and RNA-Binding Proteins: Complex Interactions in Health and Neurodegenerative Diseases
bioRxiv
Phosphorylation sites are evolutionary checkpoints against liquid-solid transition in protein condensates
Biophysical chemistry
Shapeshifter TDP-43: Molecular mechanism of structural polymorphism, aggregation, phase separation and their modulators
bioRxiv
Condensate formation of the human RNA-binding protein SMAUG1 is controlled by its intrinsically disordered regions and interactions with 14-3-3 proteins
Nature communications
Metamorphism in TDP-43 prion-like domain determines chaperone recognition
bioRxiv
Zinc Alters the Supramolecular Organization of Nucleic Acid Complexes with Full-Length TIA1
Proceedings of the National Academy of Sciences of the United States of America
Cytosolic condensates rich in polyserine define subcellular sites of tau aggregation
Cell
Functional partitioning of transcriptional regulators by patterned charge blocks
Science bulletin
Arabidopsis AUTOPHAGY-RELATED3 (ATG3) facilitates the liquid-liquid phase separation of ATG8e to promote autophagy
The Journal of biological chemistry
A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity
Nature communications
Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expanded conformations
Molecular neurodegeneration
Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy
Bioscience trends
How do RNA binding proteins trigger liquid-liquid phase separation in human health and diseases?
Communications biology
Arg/Lys-containing IDRs are cryptic binding domains for ATP and nucleic acids that interplay to modulate LLPS
bioRxiv
Different low-complexity regions of SFPQ play distinct roles in the formation of biomolecular condensates
bioRxiv
Aliphatic residues contribute significantly to the phase separation of TDP-43 C-terminal domain
The Journal of biological chemistry
Intrinsically disordered plant protein PARCL co-localizes with RNA in phase-separated condensates whose formation can be regulated by mutating the PLD
BioEssays : news and reviews in molecular, cellular and developmental biology