Nature chemistry
Most Recent
bioRxiv
Metastable condensates suppress conversion to amyloid fibrils
iScience
Heat stress promotes Arabidopsis AGO1 phase separation and association with stress granule components
bioRxiv
Expanding the molecular grammar of polar residues and arginine in FUS prion-like domain phase separation and aggregation
Nature communications
Heterotypic interactions can drive selective co-condensation of prion-like low-complexity domains of FET proteins and mammalian SWI/SNF complex
Neurobiology of disease
Casein kinase 1 inhibitor avoids TDP-43 pathology propagation in a patient-derived cellular model of amyotrophic lateral sclerosis
Biophysical journal
Structure and interactions of prion-like domains in transcription factor Efg1 phase separation
Molecular neurodegeneration
Nuclear-import receptors as gatekeepers of pathological phase transitions in ALS/FTD
bioRxiv
Sequence-specific interactions determine viscoelasticity and aging dynamics of protein condensates
Frontiers in cell and developmental biology
Two predicted α-helices within the prion-like domain of TIAR-1 play a crucial role in its association with stress granules in Caenorhabditis elegans
PLoS pathogens
Filamentation and biofilm formation are regulated by the phase-separation capacity of network transcription factors in Candida albicans
Developmental cell
Smad4 sequestered in SFPQ condensates prevents TGF-β tumor-suppressive signaling
bioRxiv
Single fluorogen imaging reveals distinct environmental and structural features of biomolecular condensates
Brain : a journal of neurology
The new missense G376V-TDP-43 variant induces late-onset distal myopathy but not amyotrophic lateral sclerosis
Communications biology
α-Synuclein emulsifies TDP-43 prion-like domain-RNA liquid droplets to promote heterotypic amyloid fibrils
The Plant cell
The m6A reader ECT1 drives mRNA sequestration to dampen salicylic acid-dependent stress responses in Arabidopsis
Cell & bioscience
Differential interactome mapping of aggregation prone/prion-like proteins under stress: novel links to stress granule biology
Aging and disease
Molecular mechanisms of phase separation and amyloidosis of ALS/FTD-linked FUS and TDP-43
bioRxiv
Heterotypic interactions in the dilute phase can drive co-condensation of prion-like low-complexity domains of FET proteins and mammalian SWI/SNF complex
Nature communications