BioRxiv
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Proteins
Thermodynamic stability of hnRNP A1 low complexity domain revealed by high-pressure NMR
bioRxiv
Consistent Force Field Captures Homolog Resolved HP1 Phase Separation
bioRxiv
Rotavirus Replication Factories Are Complex Ribonucleoprotein Condensates
Elife
Therapeutic genetic variation revealed in diverse Hsp104 homologs
Jill Bouchard
Contributing editor, Condensates.com
Here's a paper after the hearts of many in condensate therapeutics. The authors found "therapeutic genetic variation" that antagonize protein condensates.
Journal of chemical theory and computation
Simulation of FUS Protein Condensates with an Adapted Coarse-Grained Model
Science (New York, NY)
Protein condensates as aging Maxwell fluids
The journal of physical chemistry B
Molecular Details of Protein Condensates Probed by Microsecond Long Atomistic Simulations
Molecular cell
Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid
Bulletin of mathematical biology
Modeling the Mechanisms by Which Coexisting Biomolecular RNA-Protein Condensates Form
bioRxiv
Synthetic protein condensates that recruit and release protein activity in living cells
Molecular & cellular oncology
Regulation of tumorigenic splicing by protein condensates with specific biophysical properties
Jill Bouchard
Contributing editor, Condensates.com
Here's the author commentary on the 2020 Nat Cell Biol paper about how condensates are involved in splicing and tumorigenesis.
Biophysical journal
Coupled Membrane Lipid Miscibility and Phosphotyrosine-Driven Protein Condensation Phase Transitions
Jill Bouchard
Contributing editor, Condensates.com
Cool--protein droplets on membranes cause lipids to phase separate too!
bioRxiv
Coordination of RNA and protein condensation by the P granule protein MEG-3
IDPSeminars: Shana Elbaum-Garfinkle & Tim Nott — Oct 29
Thursday, October 29, 2020
bioRxiv
Charge-Driven Condensation of RNA and Proteins Suggests Broad Role of Phase Separation in Cytoplasmic Environments
BioRxiv
Understanding the phase separation characteristics of nucleocapsid protein provides a new therapeutic opportunity against SARS-CoV-2
bioRxiv
Simulation of FUS protein condensates with an adapted coarse-grained model
bioRxiv
Clustering-based positive feedback between a kinase and its substrate enables effective T-cell receptor signaling
Jill Bouchard
Contributing editor, Condensates.com
Here's a new optogenetic method to induce condensates. And the authors show they have a specific role in signalling cascades.
Biochemical Society transactions