Current opinion in cell biology
Most Recent
Trends in cell biology
Phase Separation during Germline Development
Current opinion in cell biology
Biomolecular condensates in autophagy regulation
Trends in Biochemical Sciences
FUS and TDP-43 Phases in Health and Disease
Journal of cell science
Polarisome assembly mediates actin remodeling during polarized yeast and fungal growth
Jill Bouchard
Contributing editor, Condensates.com
And the authors discuss how the phase separation of some IDRs is at the heart of this process.
Cancer cell
Biomolecular condensates and cancer
The Journal of biological chemistry
Hyperosmotic phase separation: Condensates beyond inclusions, granules and organelles
Trends in biochemical sciences
Microbial Prions: Dawn of a New Era
Trends in genetics : TIG
Speed-Specificity Trade-Offs in the Transcription Factors Search for Their Genomic Binding Sites
Jill Bouchard
Contributing editor, Condensates.com
I have a good feeling this opinion piece will discuss the role of phase separation in how IDRs of transcription factors help with both speed and specificity.
Biochimica et biophysica acta Molecular cell research
Pyrenoids: CO 2-fixing phase separated liquid organelles
Frontiers in cell and developmental biology
Complex Interactions Between Membrane-Bound Organelles, Biomolecular Condensates and the Cytoskeleton
Trends in cell biology
Biomolecular Condensates at the Front: Cell Migration Meets Phase Separation
Current opinion in cell biology
Noise buffering by biomolecular condensates in glucose sensing
Cell
Phase Separation as a Missing Mechanism for Interpretation of Disease Mutations
Virus research
Double-edged Role of PML Nuclear Bodies during Human Adenovirus Infection
International journal of molecular sciences
Intrinsic Disorder in Plant Transcription Factor Systems: Functional Implications
Physical chemistry chemical physics : PCCP
Recent advances in atomic molecular dynamics simulation of intrinsically disordered proteins
Jill Bouchard
Contributing editor, Condensates.com
For anyone getting into studying a condensate-loving IDP with in silico methods, this could be a good place to start.
Cell
Chromatin: Liquid or Solid?
Jill Bouchard
Contributing editor, Condensates.com
Here's the Preview article about the Cell paper showing that chromatin behaves like a solid.
Journal of neurochemistry
The multi-functional RNA binding protein G3BP1 and its potential implication in neurodegenerative disease
Jill Bouchard
Contributing editor, Condensates.com
This review covers G3BP1's role in phase separation and the formation of stress granules in looking for clues for how to target it therapeutically.
Biochemical Society transactions
Multifunctionality of F-rich nucleoporins
Jill Bouchard
Contributing editor, Condensates.com
I wonder if the difference in localization is due to subtle differences in phase separation propensity and/or material properties? Read on to find out.