Frontiers in synaptic neuroscience
Most Recent
bioRxiv
Dynamin forms liquid-like condensates at synapses to support ultrafast endocytosis
Frontiers in molecular biosciences
α-Synuclein in the Synaptic Vesicle Liquid Phase: Active Player or Passive Bystander?
Nature chemistry
O-GlcNAcylation modulates liquid-liquid phase separation of SynGAP/PSD-95
Journal of molecular biology
Interactions between membraneless condensates and membranous organelles at the presynapse: a phase separation view of synaptic vesicle cycle
Nature communications
Phase separation and zinc-induced transition modulate synaptic distribution and association of autism-linked CTTNBP2 and SHANK3
Current opinion in neurobiology
Re-examination of the determinants of synaptic strength from the perspective of superresolution imaging
iScience
Bidirectional protein-protein interactions control liquid-liquid phase separation of PSD-95 and its interaction partners
Open biology
Protein phase separation hotspots at the presynapse
Translational cancer research
Advances in the phase separation-organized membraneless organelles in cells: a narrative review
Frontiers in physiology
Regulation of the Stability and Localization of Post-synaptic Membrane Proteins by Liquid-Liquid Phase Separation
BioRxiv
Btbd11 is an inhibitory interneuron specific synaptic scaffolding protein that supports excitatory synapse structure and function
National Science Review
An interview with Mingjie Zhang: phase separation in biological systems
Molecular psychiatry
Modifying the m 6 A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging
Jill Bouchard
Editor in Chief, Condensates.com
The authors think LLPS may be involved in this process. I bet they're already working on experiments to know for sure.
Biophysical journal
Assembly of Model Postsynaptic Densities Involves Interactions Auxiliary to Stoichiometric Binding
Jill Bouchard
Editor in Chief, Condensates.com
Here's a mean-field LLPS theory to predict phase behavior.
Proceedings of the National Academy of Sciences of the United States of America
Surface densities prewet a near-critical membrane
Jill Bouchard
Editor in Chief, Condensates.com
These authors analyzed the physics of membrane-associated condensates. Interesting stuff!
Nov
01
ONLINE–Cell Symposia: Biological Assemblies: Phase Transitions and More
Monday, November 1, 2021
Molecular brain
Multivalent electrostatic pi-cation interaction between synaptophysin and synapsin is responsible for the coacervation
Journal of molecular biology
Liquid-liquid phase separation at the plasma membrane-cytosol interface: common players in adhesion, motility, and synaptic function
Neuroscience research
Molecular mechanism of hippocampal long-term potentiation – Towards multiscale understanding of learning and memory
Jill Bouchard
Editor in Chief, Condensates.com
This work shows CaMKII can phase separate at the synapse.