Nature Communications
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Must ReadVIDEO: René Ketting on The Role of Germ Granules in Small RNA Pathways
Journal of molecular biology
Phase Separation in Biology and Disease; Current Perspectives and Open Questions
Cell Death and Differentiation
CD-NTase family member MB21D2 promotes cGAS-mediated antiviral and antitumor immunity
bioRxiv
Structure and DNA bridging activity of the essential Rec114-Mei4 trimer interface
Pharmacological Research
Twist1-YY1-p300 complex promotes the malignant progression of HCC through activation of miR-9 by forming phase-separated condensates at super-enhancers and relieved by Metformin
Cell stress & chaperones
The association and clinical relevance of phase-separating protein CAPRIN1 with noncoding RNA
International Journal of Biological Macromolecules
Phosphorylation and specific DNA improved the incorporation ability of p53 into functional condensates
Journal of cell science
Incorporation of 53BP1 into phase-separated bodies in cancer cells during aberrant mitosis
Zoological research
Current understanding of the cGAS-STING signaling pathway: Structure, regulatory mechanisms, and related diseases
Proceedings of the National Academy of Sciences of the United States of America
Inhibiting androgen receptor splice variants with cysteine-selective irreversible covalent inhibitors to treat prostate cancer
Nucleic acids research
Dynamic phase separation of the androgen receptor and its coactivators key to regulate gene expression
Stem cell reviews and reports
Amyotrophic Lateral Sclerosis, FUS and Protein Synthesis Defects
bioRxiv
Shift of the insoluble content of the proteome in aging mouse brain
bioRxiv
Optogenetic clustering and membrane translocation of the BcLOV4 photoreceptor
Cancer science
HNF1B-driven three-dimensional chromatin structure for molecular classification in pancreatic cancers
bioRxiv
Transcription factor clusters enable target search but do not contribute to target gene activation
International journal of molecular sciences
The Involvement of Long Non-Coding RNAs in Glutamine-Metabolic Reprogramming and Therapeutic Resistance in Cancer
International journal of molecular sciences
Unveiling the Metal-Dependent Aggregation Properties of the C-terminal Region of Amyloidogenic Intrinsically Disordered Protein Isoforms DPF3b and DPF3a
Cancer informatics