Dec
02
IDPSeminars: Monika Fuxreiter & Hao Jiang — December 2
Thursday, December 2, 2021
Most Recent
Viruses
The HIV-1 Nucleocapsid Regulates Its Own Condensation by Phase-Separated Activity-Enhancing Sequestration of the Viral Protease during Maturation
Cells
SUMO Interacting Motifs: Structure and Function
Journal of materials chemistry B
Coacervate microdroplet protocell-mediated gene transfection for nitric oxide production and induction of cell apoptosis
Cell proliferation
YTHDF1 promotes mRNA degradation via YTHDF1-AGO2 interaction and phase separation
bioRxiv
cNap1 bridges centriole contact sites to maintain centrosome cohesion
Nature communications
Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities
Journal of clinical laboratory analysis
A novel model based on liquid-liquid phase separation-Related genes correlates immune microenvironment profiles and predicts prognosis of lung squamous cell carcinoma
Molecular cell
Disordered and dead, but in good company: How a catalytically inactive UTX retains its function
Jill Bouchard
Managing editor, Condensates.com
Here's a Spotlight article about the recent Nature paper on UTX condensation.
Molecular therapy oncolytics
hnRNPK-derived cell-penetratingpeptide inhibits cancer cell survival
BioRxiv
Spatial organization of chromosomes leads to heterogeneous chromatin motion and drives the liquid- or gel-like dynamical behavior of chromatin
Annals of the New York Academy of Sciences
Noncoding RNAs: biology and applications-a Keystone Symposia report
FEBS letters
SARS-CoV-2 nucleocapsid protein interacts with immunoregulators and stress granules and phase separates to form liquid droplets
International journal of molecular sciences
p53 Transactivation Domain Mediates Binding and Phase Separation with Poly-PR/GR
Signal transduction and targeted therapy
Managing stress granule disassembly with ubiquitin and its cousin
Jill Bouchard
Managing editor, Condensates.com
Here's a Research Highlight about the two recent Science papers showing how ubiquitination of G3BP1 mediates stress granules and how ubiquitination is essential for heat-shock recovery.
Cellular & molecular biology letters
The low-complexity domains of the KMT2D protein regulate histone monomethylation transcription to facilitate pancreatic cancer progression
Nature communications
rRNA biogenesis regulates mouse 2C-like state by 3D structure reorganization of peri-nucleolar heterochromatin
BioRxiv
ATM-dependent formation of a novel chromatin compartment regulates the Response to DNA Double Strand Breaks and the biogenesis of translocations
Talanta
γ-Glutamyl transpeptidase-activated indole-quinolinium based cyanine as a fluorescence turn-on nucleolus-targeting probe for cancer cell detection and inhibition
Nucleic acids research