Nov
01
ONLINE–Cell Symposia: Biological Assemblies: Phase Transitions and More
Monday, November 1, 2021
Most Recent
Molecular cell
Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Pharmacological Inhibition of Core Regulatory Circuitry Liquid-liquid Phase Separation Suppresses Metastasis and Chemoresistance in Osteosarcoma
Kitchen Table Talk
Must ReadVIDEO: Keren Lasker on Biomolecular Condensates in Bacteria: Mechanisms and Synthetic Biology
Cell reports
A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells
Cancer science
Selective Autophagy
Jill Bouchard
Managing editor, Condensates.com
This review covers the role of phase separation in selectively degrading specific cellular components. Check it out for all the details.
Nucleic Acids Research
Cooperative DNA binding mediated by KicGAS/ORF52 oligomerization allows inhibition of DNA-induced phase separation and activation of cGAS
Science Advances
Single-molecule measurements reveal that PARP1 condenses DNA by loop stabilization
Biomedical research (Tokyo, Japan)
RNA impacts formation of biomolecular condensates in the nucleus
bioRxiv
SATB1 undergoes isoform-specific phase transitions in T cells
Molecular cell
Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation
Trends in pharmacological sciences
Liquid-liquid phase separation: a principal organizer of the cell’s biochemical activity architecture
International journal of molecular sciences
A Proteomic Study Suggests Stress Granules as New Potential Actors in Radiation-Induced Bystander Effects
Computational and structural biotechnology journal
Insight into membraneless organelles and their associated proteins: Drivers, Clients and Regulators
eLife
Identification of abscission checkpoint bodies as structures that regulate ESCRT factors to control abscission timing
Jill Bouchard
Managing editor, Condensates.com
ACBs, could they be the newest membraneless organelle on the block?
Sep
15
Broder Schmidt on Targeting Intrinsically Disordered Proteins (IDPs): In the Pack vs. the Lone Wolf
Wednesday, September 15, 2021
Biochimie
The role of G-Quadruplex DNA in Paraspeckle formation in cancer
Nucleic acids research
Why structure and chain length matter: on the biological significance underlying the structural heterogeneity of poly(ADP-ribose)
Current opinion in structural biology
Phase separation in transcription factor dynamics and chromatin organization
BioRxiv
The NDP52/CALCOCO2 selective autophagy receptor controls processing body disassembly
Jill Bouchard
Managing editor, Condensates.com
This is the first of 2 papers this week that discuss the role of P bodies in viral infections. Check out the other paper about P bodies and influenza A virus replication here.